猪链球菌病是由猪链球菌(Streptococcus suis,S.suis)引起的一种急性、热性传染病,被我国农业部列为二类动物疫病[1],脑膜炎则是2型猪链球菌(S.suis serotype 2,SS2)引起的主要病症之一,该病症在猪和人均可发生,症状重剧,死亡率高,后遗症严重[2]。此外,SS2还可引起败血症、心内膜炎,关节炎等其他病症。近年来脑膜炎型猪链球菌病的比例有明显上升趋势[3-4]。对于人类,猪链球菌的威 Streptococcus suis is an acute and hot infectious disease caused by Streptococcus suis (S. suis), classified as a second class of animal diseases by the Ministry of Agriculture [1], meningitis is a type 2 pig chain One of the major diseases caused by S.suis serotype 2 (SS2), which can occur in pigs and in per capita people, has severe symptoms, high mortality and severe sequela [2]. In addition, SS2 can cause sepsis, endocarditis, arthritis and other diseases. In recent years, the proportion of meningitis-type swine streptococcal disease has shown a clear upward trend [3-4]. For humans, Streptococcus suis Granville