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目的探讨长春西汀治疗急性脑梗死患者的临床治疗效果。方法选取2011年6月至2015年6月长春一汽总医院收治的急性脑梗死患者234例为研究对象,按治疗方法不同分为观察组和对照组,每组117例。观察组患者给予长春西汀治疗,对照组患者给予舒血宁治疗,比较两组患者的神经功能缺损积分、治疗效果和不良反应。结果观察组患者治疗后神经功能缺损积分为(11±4)分,明显优于对照组的(15±4)分,差异有统计学意义(P<0.05);观察组患者治疗有效率为91.5%,明显高于对照组的73.5%,差异有统计学意义(P<0.05);观察组1例患者出现轻度皮疹,1例出现轻度恶心,不良反应发生率为1.7%,对照组患者无1例出现不良反应,两组患者不良反应发生率差异无统计学意义(P>0.05)。结论长春西汀治疗急性脑梗死疗效满意,改善了患者的脑部血流量,加速了患者的神经功能恢复,不良反应少。
Objective To investigate the clinical effect of vinpocetine in patients with acute cerebral infarction. Methods A total of 234 patients with acute cerebral infarction who were admitted to Changchun FAW General Hospital from June 2011 to June 2015 were selected as study subjects and divided into observation group and control group with 117 cases in each group. Patients in the observation group were treated with vinpocetine, while patients in the control group were treated with Shuxuening. Neurological deficit scores, treatment effects and adverse reactions were compared between the two groups. Results The score of neurological deficit in observation group was (11 ± 4) points after treatment, which was significantly better than that of control group (15 ± 4), the difference was statistically significant (P <0.05). The treatment effective rate in observation group was 91.5 %, Which was significantly higher than that of the control group (73.5%, P <0.05). In the observation group, 1 patient had mild rash, 1 patient had mild nausea, and the incidence of adverse reactions was 1.7% No adverse reactions occurred in 1 patient. There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Vinpocetine has a satisfactory curative effect on acute cerebral infarction, improves the brain blood flow of patients, accelerates the recovery of neurological function, and has few adverse reactions.