论文部分内容阅读
目的:探讨2型糖尿病并发糖尿病足(DF)的好发因素及其引起DF的原因。方法:回顾性研究55例并发DF(DF组)和126例未并发DF(NDF组)的2型糖尿病患者资料,分析两组患者糖尿病发病年龄、糖尿病病程、收缩压、血液代谢指标、踝肱指数、糖尿病并发症发生情况等与糖尿病足的发生关系。结果:DF组糖尿病平均发病年龄明显高于NDF组(P<0.01);平均糖尿病病程明显长于NDF组(P<0.01);平均收缩压明显高于NDF组(P<0.05);DF组空腹血糖、糖化血红蛋白、血尿酸、血总胆固醇、低密度脂蛋白等平均值均明显高于NDF组(P<0.05);踝肱指数检测中,DF组中、重度闭塞率明显高于NDF组(P<0.05),而DF组踝肱指数正常患者比例明显少于NDF组(P<0.05);DF组冠心病、视网膜病变、肾病、周围神经病变发生率均明显高于NDF组(P<0.05)。结论:2型糖尿病并发DF时常有明确的相关发生因素,因而有必要对2型糖尿病患者进行针对性健康教育,以利于预防和减少DF的发生和发展。
Objective: To investigate the factors that cause type 2 diabetic patients complicated with diabetic foot (DF) and their causes. Methods: The data of 55 patients with type 2 diabetes mellitus (DF) and 126 patients without DF (NDF) were retrospectively analyzed. The age of onset of diabetes, duration of diabetes mellitus, systolic blood pressure, blood metabolic parameters, ankle brachial index Index, the incidence of complications such as diabetes and diabetic foot relationship. Results: The mean age at onset of diabetes in DF group was significantly higher than that in NDF group (P <0.01). The mean duration of diabetes was significantly longer than that of NDF group (P <0.01), mean systolic pressure was significantly higher than that of NDF group (P <0.05) , HbAlc, serum total cholesterol and LDL were significantly higher than those in NDF group (P <0.05). In the ankle-brachial index test, the rate of moderate and severe occlusion in DF group was significantly higher than that in NDF group (P <0.05). The incidence of coronary artery disease, retinopathy, nephropathy and peripheral neuropathy in DF group was significantly higher than that in NDF group (P <0.05) . Conclusion: Type 2 diabetes mellitus complicated with DF often have definite related factors, so it is necessary to carry out targeted health education in patients with type 2 diabetes in order to prevent and reduce the occurrence and development of DF.