作者研究了人参皂苷 Rg_2对在蟾蜍卵母细胞中表达的人神经元同侧和异侧烟碱性乙酰胆碱受体(nAChRs)的影响。将人参皂苷 Rg_2粉末溶于二甲亚砜制成200 mmol/L 的储备液,ACh 溶液须新鲜配制。蟾蜍卵母细胞用改性林格氏溶液灌流,保持电压-80mV,电流以50Hz 的频率通过Bessel 滤波器,用电压钳对受体进行电生理测量。结果显示,100μmol/L 的 Rg_2对1 The authors studied the effects of ginsenoside Rg 2 on iNOS ipsilateral and heterologous nicotinic acetylcholine receptors (nAChRs) expressed in human oocytes. The ginsenoside Rg 2 powder was dissolved in dimethyl sulfoxide to make a stock solution of 200 mmol/L. The ACh solution must be freshly prepared. The oocytes were perfused with modified Ringer’s solution and the voltage was maintained at -80 mV. The current was passed through a Bessel filter at a frequency of 50 Hz and the receptors were electrophysiologically measured with a voltage clamp. The results showed that 100μmol/L of Rg_2 against 1