原发性IgA肾病(IgAN)是一种免疫病理定义的疾病,最显著的病理特征是以IgA为主的免疫复合物沉积于肾小球系膜区。该病的病理异质性较大,光镜下可见到接近正常结构的轻微病变,也可见到伴有新月体形成的严重增生性肾小球病变,部分患者则以局灶节段硬化样病变为主~[1]。IgAN患者临床表现差异也较大,较轻微的患者仅表现为无症 Primary IgA nephropathy (IgAN) is a disease defined by immunopathology, the most prominent of which is the deposition of IgA-based immune complexes in the mesangial area. Pathological heterogeneity of the disease larger, light microscopy can be seen near the normal structure of minor lesions, can also be seen with crescent formation of severe proliferative glomerular lesions, while some patients with focal segmental sclerosis like The main disease ~ [1]. IgAN patients also have significant differences in clinical manifestations, patients with mild only showed asymptomatic