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为探讨急性卒中病人出院后抗高血压治疗的必要性及体位性血压反应(orthostatic BP reaction)的发生率和程度,作者观察226例急性卒中病人出院后来1年的血压(BP)自然变化。这些病人在住院期间及出院后均未间断抗高血压治疗。每例病人在出院后每1、6、12个月测血压3次。观察指标为:收缩压(SBP)、舒张压(DBP)、平均动脉压(DBP+(SBP-DBP)/3),体位性BP反应。结果发现:226例病人(平均73岁),其中男128例,女98例。41％的病人有高血压史,20％有TIA和卒中史,16％有房颤史,23％有冠心病史,13％有糖尿病史。随访中,2/3的病例血压明显升高(P<0.001),出院1月与住院4天时相比,平均SBP从
To investigate the necessity of antihypertensive therapy after discharge and the incidence and extent of orthostatic BP reaction in acute stroke patients, we observed the natural BP changes of 226 acute stroke patients one year after discharge. These patients did not discontinue antihypertensive treatment during hospitalization and after discharge. Blood pressure was measured 3 times for each patient at 1, 6, and 12 months after discharge. The observed indexes were SBP, DBP and SBP-DBP / 3, postural BP. The results showed that: 226 patients (average 73 years), including 128 males and 98 females. 41% had a history of hypertension, 20% had a history of TIA and stroke, 16% had a history of atrial fibrillation, 23% had a history of coronary heart disease, and 13% had a history of diabetes. At follow-up, two-thirds of patients had significantly higher blood pressure (P <0.001), and the mean SBP from January to January at hospitalization