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目的:观察一氧化氮(NO)在家兔急性心肌梗塞中的动态变化.方法:家兔8只,制备急性心肌梗塞模型,分别于缺血前、缺血即刻、缺血后1,3,6H抽血,利用镉?铜还原法测定每个时点的NO水平,借助计算机图像分析系统计算梗塞面积.结果:缺血开始后,NO迅速下降,与缺血前相比,P＜0.01;缺血后3~6HNO又有所回升,但仍远低于缺血前水平(P＜0.05).结论:在家兔实验性急性心肌梗塞中,NO总水平是降低的,其机理可能与氧分压下降、内皮细胞功能受损及酸中毒等因素有关.“,”Objective:We were to observe the dynamic changes of nitric oxide (NO) in myocardial infarction. Methods: The model of myocardial infarction was established in 8 rabbits. The reduction of copper-plated cardium was applied to measure the level of NO in plasma at the very beginning, 1,3, and 6 hours after ischemia. The area of infarction was measured through computer. Results: At the very beginning, the level of NO fell rapidly, even lower than 46%of the control; In 1-6 hours after ischemia, the level improve...