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目的探讨高频振荡通气和常频机械通气在治疗新生儿重症胎粪吸入综合征的区别。方法选择2007年10月至2009年1月我院重症胎粪吸入综合征患儿44例,其中给予高频机械通气22例(高频组),常频机械通气22例(常频组)。比较两组患儿的上机时间、上机后2h吸入氧浓度的变化、动脉氧分压与吸入氧浓度的比值、住院时间。结果高频组与常频组上机时间、上机后2h吸入氧浓度的变化、动脉氧分压与吸入氧浓度的比值、住院时间比较,差异均无统计学意义(均P>0.05)。结论高频振荡通气和常频机械通气用于治疗新生儿重症胎粪吸入综合征时,前者并未显示出优越性。
Objective To investigate the difference between neonatal severe meconium aspiration syndrome by high-frequency oscillatory ventilation and common-frequency mechanical ventilation. Methods From October 2007 to January 2009, 44 children with severe meconium aspiration syndrome were admitted to our hospital. Among them, 22 cases were given high-frequency mechanical ventilation (high-frequency group) and 22 cases were given constant-frequency mechanical ventilation (common-frequency group). Comparison of two groups of children on the machine time, on the machine 2h inhaled oxygen concentration changes, arterial oxygen pressure and inhaled oxygen concentration ratio, hospital stay. Results There was no significant difference in uptime, frequency of inhaled oxygen at 2h after operation, and ratio of arterial oxygen pressure to inhaled oxygen concentration and length of hospital stay (all P> 0.05). Conclusions High frequency oscillatory ventilation and frequent mechanical ventilation are not effective in treating neonatal severe meconium aspiration syndrome.