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目的观察复方肾炎片联合贝那普利治疗慢性肾炎蛋白尿的疗效。方法将58例肾功能正常的慢性肾炎患者分为贝那普利(ACEI组)和复方肾炎片联合贝那普利组(联合组),分别检测两组治疗前后24h尿蛋白定量、血压、血肌酐。结果治疗4个月后,联合组临床疗效总有效率(82.76%)显著高于贝那普利组(68.97%)(P<0.05),联合组的24h尿蛋白低于ACEI组(P<0.05),血压、血肌酐两组差异无统计学意义(P>0.05)。结论复方肾炎片联合贝那普利比单用贝那普利能更有效地降低慢性肾炎患者蛋白尿,且安全可靠。
Objective To observe the curative effect of compound nephritis tablets and benazepril on chronic nephritis proteinuria. Methods 58 patients with chronic nephritis with normal renal function were divided into benazepril group (ACEI group) and compound nephritis tablets combined with benazepril group (combination group), 24 h urinary protein excretion, blood pressure, blood Creatinine. Results After 4 months of treatment, the total effective rate (82.76%) in the combination group was significantly higher than that in the benazepril group (68.97%) (P <0.05) ), Blood pressure, serum creatinine was no significant difference between the two groups (P> 0.05). Conclusion Compound nephritis tablets combined with benazepril than benazepril alone can more effectively reduce proteinuria in patients with chronic nephritis, and safe and reliable.