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目的 研究综合护理提高肾病综合征患者用药依从性的效果?方法 将2019年2月至2020年6月到我院治疗的82例肾病综合征患者分为观察组(41例)和对照组(41例)?分别对两组患者配合综合护理和常规护理,比较两组护理效果?结果 ①观察组(40例,占97.56%)患者的用药依从性高于对照组(33例,占80.49%)(P<0.05)?②观察组(38例,占92.68%)的治疗总有效率高于对照组(30例,占73.17%)(P<0.05)?③观察组(3例,占7.32%)患者出现并发症的概率明显比对照组(12例,占29“,”Objective To study the effect of comprehensive nursing on improving medication compliance of patients with nephrotic syndrome. Methods The 82 patients with nephrotic syndrome who came to our hospital for treatment from February 2019 to June 2020 were divided into observation group (41 cases) and control group (41 cases). The two groups of patients were matched with comprehensive nursing and routine nursing, to compare the nursing effects of the two groups Results (1) The medication compliance of the observation group (40 cases, accounting for 97.56%) was higher than that of the control group (33 cases, accounting for 80.49%) (P<0.05). (2) The observation group (38 cases, accounting for 92.68%) the total effective rate of treatment was higher than that of the control group (30 cases, accounting for 73.17%) (P<0.05). (3) Observation group (3 cases, accounting for 7.32%) the probability of complications was significantly lower than that of the control group (12 cases, accounting for 29.27%) (P<0.05). (4) After nursing, the improvement effect of anxiety and depression in the observation group was better than that in the control group, the sleep quality was better than that of the control group (P<0.05). (5) The improvement effect of serum creatinine, serum albumin and urea nitrogen levels of patients in the observation group after nursing was better than that of the control group (P<0.05). Conclusion The application of comprehensive nursing measures in the intervention process for patients with nephrotic syndrome can improve the compliance of patients with medication, which plays an important role in improving the total effective rate of treatment of patients, and can reduce the overall incidence of complications and improve patients\' bad mood and sleep quality, and improve the patient\'s renal function, is a high-quality nursing method.