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大黄(庶虫)虫丸始载《金匮要略·血痹虚劳脉证并治》篇,近年来在临床上运用较多,有独特疗效,兹综述如下: 一 药理研究 1.对实验性肝损伤的保护作用。邱氏用四氯化碳、乙醇综合法造成大白鼠慢性肝损伤,分组观察大黄(庶虫)虫丸的影响,结果给药组LPH_5和SGPT降低,血清蛋白回升,r—球蛋白下降,肝胶原明显减少,药理改变减轻,提示大黄(庶虫)虫丸对慢性肝损伤有保护作用。用四氯化碳造成急性肝损伤,分组观察,结果表明大黄(庶虫)虫丸对急性肝损伤,无明显保护作用。
Rhubarb (Pesticide) Pills has contained articles on “Golden Chambers, Gallbladder Syndrome, and Blood Stasis Syndrome.” In recent years, they have been used in clinical practice and have unique curative effects. They are summarized as follows: 1. Pharmacological studies 1. Experimental Liver injury protection. Kou’s chronic liver injury was induced in rats by a combination of carbon tetrachloride and ethanol. The effect of rhubarb (Zhongchong) Pills was observed in groups. As a result, LPH_5 and SGPT in the treated group decreased, serum protein increased, and r-globin decreased. The collagen was significantly reduced and the pharmacological changes were alleviated, suggesting that the rhubarb (Zhongchong) Pill has a protective effect on chronic liver injury. Acute liver injury caused by carbon tetrachloride was observed in groups. The results showed that there was no obvious protective effect of rhubarb (Pesticide) Pill on acute liver injury.