论文部分内容阅读
目的观察新生儿时期的家族性渗出性玻璃体视网膜病变(Familial Exudative Vitreoretinopathy,FEVR)的发病状况及临床特征。方法回顾性分析于2014年1月至2016年3月在我院行Retcam眼底筛查中被临床诊断为FEVR的103例169眼的临床资料。结果 16446例新生儿中发现FEVR病变103例,发生率为0.63%。其中有3例(2.91%)是早产或低出生体重儿。103例169眼中,1期156眼(92.31),2期9眼(5.33%),4期4眼(2.36%),3期及5期均未见(0%)。大多数(92.31%)患者病情好转或趋于稳定,随访观察,需要激光治疗的5例9眼,占5.33%。结论(1)FEVR和早产儿视网膜病变的临床特征非常相似,其鉴别诊断需进一步完善。(2)大部分患儿属于FEVR的早期,暂不需治疗,但也有部分需要尽快进一步治疗,挽救患儿视力。
Objective To observe the incidence and clinical features of familial exudative vitreoretinopathy (FEVR) in neonatal period. Methods The clinical data of 103 eyes (169 eyes) diagnosed as FEVR from January 2014 to March 2016 in our hospital for Retcam fundus screening were retrospectively analyzed. Results A total of 103 FEVR lesions were found in 16 446 newborns, the incidence was 0.63%. Three of them (2.91%) were premature or low birth weight children. Among the 103 eyes (169 eyes), there were 156 eyes in one stage (92.31), two eyes in nine eyes (5.33%), the fourth eyes in four eyes (2.36%) and the third and fifth eyes in none (0%). The majority of patients (92.31%) got better or stabilized. Follow-up observation showed that 5 cases (9 eyes) needed laser treatment, accounting for 5.33%. Conclusions (1) The clinical features of FEVR and retinopathy of prematurity are very similar, and the differential diagnosis needs to be further improved. (2) The majority of children are early FEVR, temporarily without treatment, but there are some need to be further treated as soon as possible to save children’s vision.