毛喉萜(Forskolin)在较大剂量时对哺乳动物心肌具有正性肌力作用,同时可降低血压,故受到重视。实验证明,本品能提高大鼠、家兔和豚鼠等动物心肌的腺苷酸环化酶活性,但对β肾上腺素受体无激动作用,故认为它增强心肌收缩力的作用是因为直接提高心肌内 Forskolin has a positive inotropic effect on mammalian myocardium at higher doses, and at the same time can lower blood pressure. Therefore, attention is paid to Forskolin. Experiments show that this product can improve adenylyl cyclase activity in rat, rabbit and guinea pigs and other animals, but no agonism of β-adrenoceptor, it is believed that its role in enhancing myocardial contractility because of direct increase Myocardial