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目的探讨大剂量甲基强的松龙在急性脊髓炎患者中的应用效果。方法选择急性脊髓炎患者共80例,随机分为观察组和对照组。观察组给予大剂量甲基强的松龙冲击治疗,对照组给予氢化可的松常规治疗。观察两组患者肌力和感觉恢复情况。结果观察组肌力改善时间短于对照组(P<0.05);观察组感觉恢复时间短于对照组(P<0.05);观察组排尿恢复时间短于对照组(P<0.05);观察组下床行走时间短于对照组(P<0.05);观察组住院时间短于对照组(P<0.05)。观察组总有效率高于对照组(P<0.05)。结论大剂量甲基强的松龙冲击治疗急性脊髓炎疗效显著,能够在较短时间改善患者肌力和感觉障碍,值得借鉴。
Objective To investigate the effect of high-dose methylprednisolone in patients with acute myelitis. Methods A total of 80 patients with acute myelitis were randomly divided into observation group and control group. The observation group was given high dose methylprednisolone impact treatment, and the control group was given routine hydrocortisone treatment. The muscle strength and sensory recovery of the two groups were observed. Results The improvement time of muscle strength in the observation group was shorter than that in the control group (P <0.05). The sensory recovery time in the observation group was shorter than that in the control group (P <0.05). Urination recovery time in the observation group was shorter than that in the control group (P <0.05) The walking time in bed was shorter than that in control group (P <0.05). The hospitalization time in observation group was shorter than that in control group (P <0.05). The total effective rate in observation group was higher than that in control group (P <0.05). Conclusion High doses of methylprednisolone shock treatment of acute myelitis significant effect, in a relatively short period of time to improve muscle strength and sensory disturbances, is worth learning.