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本文运用噻唑蓝比色法。间接免疫荧光法测定了３１引例晚期卵巢癌患者的外周血淋巴细胞（ＰＢＬ）、腹水淋巴细胞（ＥＡＬ）及肿瘤浸润淋巴细胞（ＴＩＬ）的ＮＫ活性和细胞亚群，并对常规手术、化疗对肿瘤患者免疫功能的影响进行初步探讨。结果：卵巢癌患者的ＰＢＬＮＫ活性明显低于正常和良性钟瘤组，其中ＣＤ＋３、ＣＤ＋４及Ｂ细胞较少，ＣＤ＋４／ＣＤ８＋比值较低；而ＴＩＬ的ＮＫ活性较ＰＢＬ更为低下，其ＣＤ＋４／ＣＤ＋８严重失衡。推测：卵巢癌患者机体免疫功能全面受抑，尤以局部明显；传统手术、化疗同辅以增强免疫的支持治疗有望改善患者预后。
This article uses thiazole blue colorimetric method. Indirect immunofluorescence assay was used to determine the NK activity and cell subsets of peripheral blood lymphocytes (PBLs), ascites lymphocytes (EALs) and tumor infiltrating lymphocytes (TILs) in 31 patients with advanced ovarian cancer. The routine operation and chemotherapy Tumor patients with immune function to conduct a preliminary study. Results: The activity of PBLNK in patients with ovarian cancer was significantly lower than that in normal and benign group. There were less CD + 3, CD + 4 and B cells and lower CD + 4 / CD8 + ratio. TIL had lower NK activity than PBL. CD + 4 / CD + 8 Serious imbalance. Speculated that: the immune function of patients with ovarian cancer was completely suppressed, especially in local obvious; traditional surgery, chemotherapy and adjuvant to enhance immune support is expected to improve the prognosis of patients.