近年来,有机小分子催化取得了快速的发展,不少报道已表明手性BrФnsted碱可作为一系列不对称反应中的高效催化剂[1].然而,常见的手性BrФnsted碱催化剂的碱性官能团却往往受限于三级胺、脒基、胍基以及最近报道的环丙基亚胺和亚胺基膦基团等,主要结构骨架也往往是金鸡纳碱、双官能团硫脲以及联萘衍生物等.因此,探索和发展具有新型结构的BrФnsted碱将为不对称催化带来全新的机遇. In recent years, the rapid development of organic small molecule catalysis has been achieved, and many reports have shown that chiral Brønsted base can be used as a series of asymmetric reactions in the efficient catalyst [1] However, the common chiral BrФnsted base catalyst basic functional groups Is often limited to tertiary amines, amidino, guanidino and recently reported cyclopropylimine and iminophosphine groups. The main structural skeleton is also often cinchina, bifunctional thiourea and binaphthyl derivatives Etc. Therefore, exploring and developing a Brφnsted base with a novel structure will bring about entirely new opportunities for asymmetric catalysis.