近来的研究表明:C-onc 基因或经病毒基因组的插入,或经基因放大,染色体易位均可导致人类和动物恶性肿瘤的产生。C-myb 和C-fes 分别为鸟类成髓细胞增多症病毒和猫类肉瘤病毒的转化基因之类似物.C-myb 优先在未成熟的造血细胞中转录和编码 Recent studies have shown that insertion of the C-onc gene, either by the viral genome or by gene amplification, can result in malignant tumors in both humans and animals. C-myb and C-fes are analogs of the transformed genes of avian myeloblastosis virus and feline sarcoma virus, respectively. C-myb is preferentially transcribed and encoded in immature hematopoietic cells.