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目的：探讨肠球菌所致急性肾盂肾炎的耐药性基因，探讨治疗对策，指导临床合理用药。方法选取我院2012年5月~2013年6月收治的有肠球菌导致的急性肾盂肾炎患者常规培养检出148株肠球菌为研究对象，分析其耐药性。结果148株肠球菌属构成比例为：粪肠球菌72株（48.65%）；尿肠球菌55株（37.16%）；鸟肠球菌17株（11.49%）；其他肠球菌4株（2.70%）。粪肠球菌对利福平、四环素、红霉素耐药率＞70%。尿肠球菌对左氧氟沙星、青霉素、安卡西林、红霉素、呋喃妥因耐药率达到70%以上。尿肠球菌对红霉素、氨苄西林耐药率达到70%以上。结论随着社会的发展和一些用药的不同，肠球菌的耐药性也在不断的增强，而且肠球菌也有很多种不同的类型，就它的这种中间差异性来说，一些抗生素的耐药性也不同，这也是如今比较严重的问题，在此同时也预示着临床上药根据肠球菌的耐药不同，来有针对性的去选择抗生素。药物的使用在不断的增多，药物的药效也在逐渐的增强，由此导致肠球菌不断地演变，分化的菌种类型增多，其耐药性也不断的增强，因此在治疗肠球菌所引发的疾病时，应根据不同肠球菌的耐药性，选择合适的治疗方法，减少临床上的治疗错误。“,”Objective:Investigate the drug resistance of enterococcus caused by acute pyelonephritis genes,treatment countermeasures is discussed,and to guide clinical rational drug use. Methods:Select our hospital from May 2012 to June 2012 treated with enterococcus in patients with acute pyelonephritis regular train detection 148 strains enterococcus as the research object,Analysis of the resistance. Results:148 strains of enterococcus belong to constitute ratio for:Dung enterococcus72strains (48.65%);Urine 55 strains enterococcus (37.16%); Bird 17 strains enterococcus (11.49%);The other 4 strains enterococcus (2.70%). Dung enterococcus of rifampicin, Tetracycline, Erythromycin resistant rate > 70%. Urine enterococcus of levofloxacin,Westwood, erythromycin,penicil in,anka,with nitrofurantoin due to resistance to reach more than 70%. Conclusion:With the development of the society and some of the medication is dif erent,The drug resistance of enterococcus have been enhanced, And also there are many dif erent types of enterococcus,Is it in the middle of this dif erence,Some antibiotics resistance is dif erent also,This is serious problem nowadays,At the same time also foreshadowed the clinical prescription according to the drug resistance of enterococcus is dif erent,To targeted to choose antibiotics.Drug use is constantly increasing,the ef ects of the drug are also gradual y enhanced,leading to bowel coccus continuously evolution,increase in the number of strains of type dif erentiation,its resistance also constantly strengthen,therefore in the treatment of the diseases caused by enterococcus,should according to dif erent drug resistance of enterococcus,select the appropriate treatment,reduce the clinical medication errors.