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文献报告应用茛菪类药物治疗冠心病心绞痛、急性心肌梗塞(简称心梗)及心梗致心源性休克获得成功。但有关其作用机制的实验研究报导尚少。我们在麻醉犬观察到654-2(Anisodamine)对缺血心肌有保护作用。本文在清醒家兔模型上,用亚急性实验方法,观察654-2对急性心梗范围的影响,以期为临床提供较可靠的理论根据。
The literature report of Panax medicinal herbs in the treatment of angina pectoris, acute myocardial infarction (MI) and myocardial infarction caused by cardiogenic shock success. However, experimental studies on its mechanism of action are still rare. We observed in anesthetized dogs 654-2 (Anisodamine) has a protective effect on ischemic myocardium. In the awake rabbit model, with subacute experimental methods to observe the impact of 654-2 on the scope of acute myocardial infarction in order to provide a more reliable theoretical basis for the clinical.