论文部分内容阅读
目的探讨本地区正常足月新生儿的黄疸发生时间、血清胆红素峰值(SB)及峰值出现时间,并寻求部分因素与新生儿高胆红素血症的相关性。方法采用国产HD-368型经皮胆红素测定仪对960例足月新生儿的血清胆红素浓度进行生后1～7d的监测,并且用改良J-G法对所测胆红素浓度进行间断复核。结果发现正常足月新生儿血清胆红素峰值平均为(232±57)μmol/L,峰值出现时间为生后5d,生后24h内出现黄疸,血清胆红素浓度>102.6μmol/L者占27.84%,血清胆红素峰值>205.2μmol/L者占47.22%,>256.5μmol/L者占12.15%,>307.8μmol/L者占1.47%。并指出新生儿高胆红素血症与下列因素相关:剖宫产(χ2=27.08,P<0.01)、母亲使用催产素(χ2=21.56,P<0.01)、新生儿体重下降偏多(≥7%)(χ2=38.31,P<0.01),而与性别无关(χ2=1.12,P>0.01)。新生儿窒息后高胆红素血症发生率并不增加(χ2=l.02,P>0.01)。结论新生儿保质、保量、合理的母乳喂养是降低高胆红素血症发生率的关键之一,孕母慎用催产素为其二。但是,对正常新生儿和窒息儿的黄疸治疗标准是否可适当增高有待进一步研究。
Objective To investigate the occurrence of jaundice, the peak of serum bilirubin (SB) and peak time of newborn infants with normal full term in this area, and to find the correlation between some factors and neonatal hyperbilirubinemia. Methods The serum bilirubin concentration of 960 full-term newborns was monitored 1 to 7 days after birth by a domestic HD-368 transcutaneous bilirubin analyzer, and the measured bilirubin concentration was interrupted by the modified JG method Review. The results showed that the mean peak serum bilirubin in normal full-term neonates was (232 ± 57) μmol / L, peak appearance time was 5 days after birth, jaundice within 24 hours after birth, serum bilirubin concentrations> 102.6μmol / L 27.84%, peak serum bilirubin> 205.2μmol / L accounted for 47.22%,> 256.5μmol / L accounted for 12.15%,> 307.8μmol / L accounted for 1.47%. And pointed out that neonatal hyperbilirubinemia is associated with the following factors: cesarean section (χ2 = 27.08, P <0.01), mother using oxytocin (χ2 = 21.56, P <0.01) 7%) (χ2 = 38.31, P <0.01), but not gender (χ2 = 1.12, P> 0.01). Neonatal asphyxia did not increase the incidence of hyperbilirubinemia (χ2 = l.02, P> 0.01). Conclusion Neonatal quality, quantity, reasonable breastfeeding is one of the keys to reduce the incidence of hyperbilirubinemia, pregnant women cautiously use oxytocin as the second. However, the normal neonatal and asphyxia jaundice treatment standards can be properly increased for further study.