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宫腔粘连(IUA)对女性的身体及心理造成不同程度的伤害。宫腔镜手术能恢复宫腔正常形态,但不能修复子宫内膜,从而造成再粘连的发生。有研究显示,行宫腔镜宫腔粘连分离的患者术后再粘连的发生率为3.1%~23.5%。雌激素能促进内膜腺体和间质细胞的增殖,促进内膜血管的生成,从而达到尽快修复创面、形成子宫壁的功能性分离,有利于新生内膜的生长。因此,IUA术后多应用雌激素预防再粘连发生,但目前关于雌激素的用法、用量并不十分统一,有待于进一步的深入研究。
Intrauterine adhesions (IUA) on women’s physical and psychological damage caused to varying degrees. Hysteroscopic surgery can restore the normal uterine morphology, but can not repair the endometrium, resulting in the occurrence of re-adhesion. Some studies have shown that hysteroscopic adhesions in patients with hysteroscopic adhesions after the incidence of 3.1% to 23.5%. Estrogen can promote the proliferation of endometrial glands and interstitial cells, and promote the formation of endothelium vessels, so as to repair the wound as soon as possible to form a functional separation of the uterine wall conducive to the growth of neointimal formation. Therefore, IUA multi estrogen postoperative prevention of re-adhesion occurred, but the current usage of estrogen, the amount is not very uniform, to be further in-depth study.