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目的:探讨血浆置换治疗高胆红素血症的临床意义。方法:67例高胆红素血症患者行血浆置换,分析其置换前后临床表现、血肝功能、血浆氨、凝血酶原时间变化。结果:血浆置换前、后患者临床表现、肝功能、血浆氨、凝血酶原时间改变比较差异有统计学意义(P<0.05)。结论:血浆置换可以作为临床治疗高胆红素血症的有效措施之一,且可以为等待肝脏移植的患者赢得时间。
Objective: To investigate the clinical significance of plasma exchange in the treatment of hyperbilirubinemia. Methods: Sixty-seven patients with hyperbilirubinemia underwent plasma exchange. The clinical manifestations, serum liver function, plasma ammonia and prothrombin time before and after replacement were analyzed. Results: Before and after plasma exchange, the clinical manifestations, liver function, plasma ammonia and prothrombin time were significantly different (P <0.05). Conclusion: Plasma exchange can be used as one of the effective measures to treat hyperbilirubinemia clinically and can win time for patients waiting for liver transplantation.