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目的 了解某军校学员诺瓦克样病毒抗体水平 ,同时调查分析与血型、入学前家庭所在地等的关系。方法 利用酶联免疫吸附试验检测血清中的诺瓦克样病毒rNV、rMX和r387特异性IgG抗体水平。结果 rNV、rMX和r387IgG抗体总检出率分别为 88 9% ,5 4 1%和 90 0 %。其中rMX抗体阳性率不同血型之间存在显著性差异 (P<0 0 5 ) ,以O型抗体阳性率最高 6 2 5 % (115 / 184 ) ,B型最低 4 9 1% (16 0 / 2 16 ) ,而rNV和r387抗体阳性率未见显著性差异。不同入学前家庭所在地 3种抗体阳性率均有显著性差异 ,其中以农村籍学员抗体阳性率最高 ,城市最低。结论 该军校人群中诺瓦克样病毒感染普遍 ,血型及入学前家庭所在地可能是影响诺瓦克样病毒抗体水平的因素
Objective To understand the level of Norwalk-like virus antibody in a cadet cadet and to investigate the relationship with blood type, pre-school home location and so on. Methods The levels of rNV, rMX and r387-specific IgG antibodies to Norwalk-like virus in serum were detected by enzyme linked immunosorbent assay (ELISA). Results The total detection rates of rNV, rMX and r387 IgG antibodies were 88.9%, 54.1% and 90.0% respectively. Among them, the positive rate of rMX antibody was significantly different between different blood groups (P <0.05). The positive rate of O-type antibody was the highest (65/215%), the lowest was 491% (16.0%) 16), but there was no significant difference in the positive rates of rNV and r387 antibodies. There were significant differences in the positive rates of the three kinds of antibodies among the families before enrollment, among which the positive rates of antibody were the highest in rural students and the lowest in cities. Conclusions Norwalk-like virus infection is common in this military population. The blood type and location of pre-school families may be the factors that influence the level of Norwalk-like virus antibodies