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据日本的一项回顾性以人群为基础的研究报道,在患结肠直肠癌的妇女中,肿瘤发生在近端结肠的老年女性比年轻女性更多。他们回顾了有组织学诊断的1205名(男655人,女550人,:平均年龄66岁)结肠直肠癌患者的资料(性别、年龄、肿瘤位置)。历时20年的时间。在研究的前10年(1975~1984年)结肠直肠癌的发病率32%,后10年(1985~1994年)升高到680%。在65岁以上病人中,近端结肠发生肿瘤占61%,较年轻病人占39%,但这一高发病率仅在妇女中明显。在前10年的研究期间,36名直肠结肠癌病人,肿瘤位置与年龄相关无统计学意义。而在后10年,819名结肠直肠癌患者中大于65岁的病人近端结肠癌的发生率高达65%,与之相比小于65岁者只有35%。
According to a retrospective population-based study in Japan, in women with colorectal cancer, there are more elderly women with tumors in the proximal colon than in young women. They reviewed data (sex, age, tumor location) of 1,205 colorectal cancer patients (655 men, 550 women, 66 men) with histological diagnosis. It took 20 years. In the first 10 years of the study (1975-1984), the incidence of colorectal cancer was 32%, and it increased to 680% in the next 10 years (1985-1994). In patients over 65 years of age, proximal colon tumors account for 61% and younger patients 39%, but this high incidence is only evident in women. During the first 10 years of the study, 36 patients with rectal colon cancer had no statistically significant differences in tumor location and age. In the next 10 years, the incidence of proximal colon cancer was as high as 65% in 819 patients with colorectal cancer who were older than 65 years, compared with only 35% in those less than 65 years old.