论文部分内容阅读
内分泌疾病中骨骼肌的病变很早就被人们所注意,但对呼吸肌功能的研究则是一个较新的课题。 从生理、生化和结构方面来看,呼吸肌和骨骼肌是一致的。大量研究证实,激素影响呼吸肌的功能。其作用机制包括:①改变呼吸肌的收缩机制;②改变呼吸肌细胞的能量供应及代谢途径;③改变呼吸肌细胞膜的通透性;④改变蛋白质的转运。本文仅对临床常见几种内分泌疾病在呼吸肌功能上的影响作一般性阐述。 在甲状腺机能亢进中,93％的患者表现为呼吸肌功能障碍。研究发现:最大口腔吸气压(P_(lmax))和最大口腔呼气压(P_(Emax))降低;血中T_3、T_4水平与P_(lmax)和P_(Emax)
Endocrine disease skeletal muscle lesions have long been people’s attention, but the study of respiratory muscle function is a relatively new issue. Respiratory and skeletal muscles are physiologically, biochemically and structurally identical. A large number of studies have confirmed that hormones affect the function of respiratory muscles. Its mechanism includes: ① change the respiratory muscle contraction mechanism; ② change the respiratory muscle cell energy supply and metabolic pathways; ③ change the respiratory muscle cell membrane permeability; ④ change the protein transport. This article only on the clinical common several endocrine diseases in respiratory muscle function for a general description. In hyperthyroidism, 93% of patients showed respiratory muscle dysfunction. The results showed that the maximum oral pressure (P_ (lmax)) and maximum oral expiratory pressure (P_ (E_max)) decreased. The levels of T_3 and T_4 in the blood were positively correlated with the values of P_ (lmax) and P_