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近年来,随着临床药理学研究的深入和临床对疾病机理研究的发展,发现了许多传统药物的临床某些新用途,为临床疾病治疗拓宽了渠道。本文做简单归纳总结。1 卡介苗治疗哮喘目前公认支气管哮喘与 IgE 介导的速发型反应和其后以多种炎细胞及介质参与的炎症反应有关。卡介苗素是卡介苗的有效成分,它能活化 T 辅助细胞,产生 r—干扰素,而 r—干扰素是 IgE 生成因子 IL—4的拮抗剂,因此可能降低IgE 的水平,治疗哮喘的发生;另外其对哮喘反应细胞膜具有稳定作用,故能防止哮喘。王春利等应用卡介苗素肌肉注射治疗小儿哮喘60例,结果单用卡介苗素就能控制症状者23例(38.8%),仍需其他药物控制症状者29例
In recent years, along with the in-depth study of clinical pharmacology and clinical research on the development of disease mechanisms, some new uses of traditional medicine have been discovered, which broaden the channels for the treatment of clinical diseases. This article briefly summarizes. 1 BCG treatment of asthma Bronchial asthma is currently recognized and IgE-mediated rapid-onset reaction followed by a variety of inflammatory cells and media involved in the inflammatory response. BCG is the active ingredient of BCG, it can activate T helper cells, produce r-interferon, and r-interferon is IgE-producing factor IL-4 antagonist, it may reduce the level of IgE, the treatment of asthma; In addition It has a stabilizing effect on the cell membrane of the asthmatic response and therefore prevents asthma. Wang Chunli and other applications of BCG intramuscular injection treatment of pediatric asthma in 60 cases, the results can be controlled by single symptoms of BCG in 23 cases (38.8%), still need other drugs to control symptoms in 29 cases