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目的 :明确 1 1 1 In-奥曲肽治疗神经内分泌瘤的毒性作用。方法 :选择经病理确诊为弥漫性神经内分泌瘤患者 8例(4男 ,4女 ) ,其中 6例为弥漫性类癌瘤 ,1例为恶性胃泌素瘤 ,1例为甲状腺髓样瘤。治疗给药 1 1 1 In-奥曲肽 1.3～ 4.6GBq(平均为 3.2 GBq)。在每次治疗后 48h内
OBJECTIVE: To clarify the toxic effects of 1 1 1 In-octreotide in the treatment of neuroendocrine tumors. Methods: Eight patients (4 males and 4 females) who were pathologically diagnosed as diffuse neuroendocrine tumors were selected. Among them, 6 were diffuse carcinoid tumors, 1 was malignant gastrinoma and 1 was medullary thyroid carcinoma. Therapeutic dosing 11.1 In-octreotide 1.3-4.6 GBq (average 3.2 GBq). Within 48h after each treatment