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目的 :探讨神经系统莱姆病的临床特征及诊断方法。方法 :采用间接免疫荧光法 (IFAT)、酶联免疫吸附试验 (ELISA)进行血清和CSF莱姆病特异性IgM、IgG抗体检测 ,同时做神经放射学、影像学和电生理检查。 结果 :4年内在神经系统疾病患者中检出莱姆病特异性IgG、IgM抗体阳性者 5 6例。 结论 :神经系统莱姆病临床表现多样化 ,当病因不明时 ,神经莱姆病应作为鉴别诊断之一 ,进行血清学检测 ,力争早发现 ,早治疗。
Objective: To investigate the clinical features and diagnosis of Lyme disease of the nervous system. Methods: Serum and CSF Lyme disease specific IgM and IgG antibodies were detected by indirect immunofluorescence (IFAT) and enzyme-linked immunosorbent assay (ELISA), and neuroradiology, radiology and electrophysiology were performed simultaneously. Results: 56 patients with Lyme disease-specific IgG and IgM antibodies were detected in patients with neurological diseases in 4 years. Conclusion: The clinical manifestation of Lyme disease of the nervous system is diversified. When the etiology is unknown, Lyme disease should be used as one of the differential diagnoses to carry out serological tests to strive for early detection and early treatment.