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卵巢癌恶性程度高，就诊时大部分患者已届晚期，为了研究卵巢癌的发生发展及生物学特性，尤其是早期变化，需要建立相应的动物模型。我们采用ＤＭＢＡ埋线法成功地建立了大鼠卵巢肿瘤模型，并初步观察了大鼠卵巢肿瘤的病理形态特征。1 材料与方法1.1 实验材料 致癌剂二甲基苯蒽
Ovarian cancer has a high degree of malignancy. Most of the patients have advanced stage of treatment. In order to study the occurrence and development of ovarian cancer and its biological characteristics, especially the early changes, it is necessary to establish the corresponding animal model. We successfully established rat ovarian tumor model by DMBA embedding method and preliminary observed the pathological features of rat ovarian tumors. 1 Materials and Methods 1.1 Experimental Materials Carcinogen dimethyl benzene anthracene