论文部分内容阅读
生物体通过指导的自组装合成种类繁多、功能特异的天然纳米结构,它们在生命过程中扮演重要角色。按照自组装体的维度,可以分为线状(一维)、层状(二维)、笼状(三维)生物纳米结构。通过设计,这些生物大分子纳米结构可在细胞“工厂”中重组制备,且可通过合成生物学技术对其组装和功能化进行理性设计和调控,成为功能性纳米器件。这类纳米生物结构和器件已经在生物传感、催化、肿瘤热疗、药物递送、组织工程、生物电池等领域获得展示或应用。相关研究正在成为合成生物学和纳米生物学的一个交叉领域,受到关注。
Organizations synthesize a wide range of natural, functional, and specific nanostructures through directed self-assembly that play an important role in life. According to the self-assembly dimension, it can be divided into linear (one-dimensional), layered (two-dimensional), cage (three-dimensional) biological nanostructures. By design, these biomacromolecular nanostructures can be recombinantly prepared in cells “factories” and functionally nanodevices can be rationally designed and regulated through their assembly and functionalization through synthetic biology techniques. Such nanobiological structures and devices have been demonstrated or applied in the fields of biosensing, catalysis, tumor hyperthermia, drug delivery, tissue engineering, bio-cells and the like. Related research is becoming a cross-section of synthetic biology and nano-biology, attention.