临床上进行同种异体组织或器官移植时,为了使移植物能够长期存活,常规使用大量的皮质激素和硫唑嘌呤等药物来抑制机体的免疫反应。这些药物虽抗移植排斥作用较强,但毒副作用过大。近年开始使的新型免疫抑制,剂环孢霉素 A 也有相当大的不良作用,如诱发 When allogeneic tissues or organs are transplanted clinically, in order to enable long-term survival of the grafts, a large number of drugs such as corticosteroids and azathioprine are conventionally used to suppress the body’s immune response. Although these drugs have strong anti-rejection effects, they have too much toxic side effects. In recent years, the new type of immunosuppressive agent, cyclosporine A, has also had considerable adverse effects, such as induction.