喹诺酮类药物是近年来治疗伤寒,尤其是耐氯霉素伤寒的有效药物,国内诺氟沙星使用普遍,而使用培氟沙星的报道不多。我院自去年始试用该药治疗伤寒,体会到其疗效确切。改善症状,清除细菌均优于氯霉素、氨苄青霉素、丁胺卡那霉素及诺氟沙星,但同时发现该药有不良反应发生。本文主要就其所致精神异常病例作一报告并予简要分析。该患者男性19岁,因伤寒收入院,入院时精神 Quinolones are effective drugs for the treatment of typhoid fever, especially chloramphenicol typhoid in recent years. Norfloxacin is commonly used in China, and the use of pefloxacin is not reported. Our hospital since the beginning of the trial of the drug treatment of typhoid fever last year, experience its exact effect. Improve symptoms, remove bacteria are better than chloramphenicol, ampicillin, amikacin and norfloxacin, but also found that the drug has adverse reactions. In this paper, we mainly make a report on the cases of abnormal psychosis and give a brief analysis. The patient, male, was 19 years old and admitted to hospital due to typhoid fever