例1 男性,48岁,农民。因鼻梁部被碎石打伤后伤口逐渐肿大隆起,不痛不痒已月余。检查:一般情况无特殊。鼻梁部可见一约1.8×1.8×0.6cm大小之结节,呈淡红色,境界清楚,中央嵌以棕褐色角质物,形似火山口,质中等硬,无明显压痛(见图1)。取正中组织活检,病理报告为角化棘皮瘤。给予5％氟尿嘧啶软膏外涂,3周后痊愈。随访二年半未复发。 Example 1 Male, 48 years old, farmer. Due to the wounded nose of the bridge of the nose, the wound became swollen and uplifted. It was no less than a month. Inspection: No special circumstances. A nodule with a size of 1.8×1.8×0.6 cm was seen on the bridge of the nose, showing a pale red color and a clear boundary. The center was covered with brown keratin. It was shaped like a crater, and it was medium hard without obvious tenderness (see Figure 1). The median biopsy was taken and the pathology report was keratoacanthoma. He was given 5% fluorouracil ointment and healed after 3 weeks. Follow-up of two and a half years without recurrence.