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[目的]观察辨证分型联合西药治疗肠易激综合征疗效。[方法]使用随机平行对照方法,将50例门诊及住院患者按掷骰子法简单随机分为两组。对照组25例匹维溴铵,50mg/次,3次/d;腹泻加复方地芬诺酯,5mg/次,2次/d;便秘加西沙必利,10mg/次,2次/d;腹胀明显加乳酸菌素片,0.8g/次,2次/d;腹痛加消旋山莨菪碱片,10mg/次,2次/d。治疗组25例肝郁脾虚予解郁止泻方(白术30g,白芍20g,防风15g,陈皮、甘草、香附制、柴胡各10g);脾虚泄泻予参苓白术散(白术、党参各20g,陈皮、白扁豆、薏苡仁、砂仁、淮山药、茯苓各10g,甘草、柴胡、桔梗各6g);气滞肠涩予柴胡厚朴汤(生地30g,甘草6g,茯苓、玄参、厚朴、枳壳、麦冬、白芍、陈皮、柴胡、木香各10g);脾肾阳虚四神丸(党参、补骨脂各15g,甘草6g,白术、吴茱萸、五味子、香附各10g);均1剂/d,水煎150m L,早晚口服;西药治疗同对照组。连续治疗7d为1疗程。观测临床症状、便常规、不良反应。连续治疗4疗程,判定疗效。[结果]治疗组痊愈18例,显效5例,无效2例,总有效率92.00%。对照组痊愈11例,显效6例,无效8例,总有效率68.00%。治疗组疗效优于对照组(P<0.05)。[结论]辨证分型联合西药治疗肠易激综合征疗效满意,无严重不良反应,值得推广。
[Objective] To observe the effect of syndrome differentiation and western medicine in treating irritable bowel syndrome. [Methods] Using randomized parallel control method, 50 outpatients and inpatients were randomly divided into two groups according to the dice method. The control group, 25 cases of pinaverium bromide, 50mg / times, 3 times / d; diarrhea plus diphenoxylate, 5mg / times, 2 times / d; constipation plus cisapride, 10mg / times, Bloating significantly increase lactobacillus tablets, 0.8g / time, 2 times / d; abdominal pain plus anti-spinosad tablets, 10mg / time, 2 times / d. Treatment group, 25 cases of liver depression spleen to relieve stagnation diarrhea side (Atractylodes 30g, white peony root 20g, wind 15g, dried tangerine peel, licorice, incense attached to the system, Bupleurum each 10g); spleen diarrhea to Shiling Baizhu San (Atractylodes, Ginseng, Chinese yam, Poria each 10g, licorice, Bupleurum, Campanulaceae 6g); Qi stagnation to Bupleurum Huitou Decoction (habitat 30g, licorice 6g, Poria, Scrophulariaceae , Magnolia officinalis, Citrus aurantium, Radix, Radix Paeoniae Alba, dried tangerine peel, Bupleurum, woody 10g each); spleen and kidney Yang Sishen pills (Codonopsis, psoralen the 15g, licorice 6g, Atractylodes, Evodia, Schisandra, With each 10g); were 1 / d, decoction 150m L, morning and evening oral; western medicine treatment with the control group. Continuous treatment 7d for a course of treatment. Observed clinical symptoms, routine, adverse reactions. Continuous treatment of 4 courses to determine the efficacy. [Result] The treatment group cured 18 cases, markedly effective in 5 cases, ineffective in 2 cases, the total effective rate was 92.00%. The control group recovered in 11 cases, markedly effective in 6 cases, 8 cases, the total effective rate 68.00%. The treatment group was better than the control group (P <0.05). [Conclusion] Syndrome differentiation combined with Western medicine in treating irritable bowel syndrome has satisfactory curative effect and no serious adverse reactions, which deserves promotion.