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为评估低出生体重儿生后早期间断鼻胃管喂养和鼻十二指肠喂养的效果 ,将 40例低出生体重儿 (出生体重 1 0 50～ 1 92 0g)随机分为间断鼻胃管喂养组和鼻十二指肠喂养组 ,两组出生体重、性别、胎龄无显著差异 (P >0 0 5)。用同一种配方乳喂养 ,记录入液量、热能、蛋白质摄入量、大便性状及喂养相关并发症 ,喂养前和喂养后 1周用ELISA法测血清视黄醇结合蛋白。结果显示 ,喂养后 1周鼻十二指肠喂养组较鼻胃管喂养组奶量、热能、蛋白质摄入量均显著增加 (P <0 0 0 1 ) ;肠道营养热能达 1 0 0kcal (kg·d)的时间、恢复出生体重时间均明显缩短 (P <0 0 5)。前者较后者血清视黄醇结合蛋白明显增加 (P <0 0 5)。两组均无腹泻、十二指肠穿孔、坏死性小肠结肠炎发生 ,鼻十二指肠喂养组较鼻胃管喂养组吸入性肺炎、高胆红素血症的发生显著减少 (P <0 0 1 )。提示低出生体重儿生后早期鼻十二指肠喂养优于鼻胃管喂养。
To assess the effect of nasogastric tube feeding and nasal duodenal feeding on early postnatal low birth weight infants, 40 low birth weight infants (birth weight of 150 ~ 1, 92Og) were randomly divided into intermittent nasogastric tube feeding Group and nasal duodenal feeding group, there was no significant difference in birth weight, sex and gestational age between the two groups (P> 0.05). Feeding with the same formula, the fluid intake, caloric intake, protein intake, stool traits and feeding related complications were recorded. Serum retinol binding protein was measured by ELISA before feeding and 1 week after feeding. The results showed that milk, heat and protein intake of nasal duodenal feeding group were significantly increased (P <0.01), nasal duodenal feeding group was higher than that of nasogastric tube feeding group kg · d), the time to restore birth weight was significantly shorter (P <0 05). The former than the latter serum retinol binding protein was significantly increased (P <0 05). No diarrhea, duodenal perforation and necrotizing enterocolitis occurred in both groups, and nasal duodenal feeding group had significantly lower incidence of hyperbilirubinemia than nasogastric feeding group (P <0. 0 1). Prompt low birth weight nasal duodenal feeding better than nasogastric feeding.