抗癌新药——盐酸比生群结构式为化学名:9,10—蒽二羧醛双(4,5—二氢—1H—咪唑—2—基)胺分子式及分子量:C_(22)H_(22)N_8·2HCl=471.47 本品由美国氰胺公司研制开发,1991年首次在美国上市,商品名为:Zantrene。药理作用 比生群为细胞生长抑制剂,抗肿瘤谱类似于阿霉素,但心脏毒性比阿霉素低。本品对乳腺癌、骨髓癌及各种转移的实体肿瘤如恶性肾细胞癌、复发的急性白血病及胃癌均有效,可完全缓解非淋巴细胞白血病。药理实验表明:利用新药人体肿瘤克隆系统的体外试验,本品对以下肿瘤有抗肿瘤活性:人体乳房癌、卵巢癌、肾癌、小细胞或大细胞肺癌、淋巴癌、急 Hydrochloric acid than the group structure for the chemical name: 9,10-anthracene dicarboxaldehyde bis (4,5-dihydro-1H-imidazol-2-yl) amine Molecular formula and molecular weight: C_ (22) H_ 22) N_8 · 2HCl = 471.47 This product was developed by the United States Cyanamide company, 1991 for the first time in the United States market, trade name: Zantrene. Pharmacological effects than the group of cell growth inhibitors, anti-tumor spectrum similar to doxorubicin, but the cardiotoxicity than doxorubicin low. The product of breast cancer, bone marrow cancer and various metastatic solid tumors such as malignant renal cell carcinoma, recurrent acute leukemia and gastric cancer are effective, can completely relieve non-lymphocytic leukemia. Pharmacological experiments show that: the use of new drug human tumor cloning system in vitro tests, the goods have anti-tumor activity on the following tumors: human breast cancer, ovarian cancer, kidney cancer, small cell or large cell lung cancer, lymphoma, acute