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采用记录大鼠每日摄食量的方法研究梭曼及抗毒药对大鼠摄食活动的影响。实验结果表明：大鼠肌注梭曼０．０３５ｍｇ／ｋｇ（０．６ＬＤ＿（５０））使当日摄食量下降３８．３％，抑制作用持续５ｄ。丘脑一下丘脑ＡＣｈＥ活力下降４９％，中毒后１０ｄ尚不能完全恢复，梭曼抑制摄食与其抑制ＡＣｈＥ活力的作用时间相一致。阿托品１０ｍｇ／ｋｇ肌注，可使大鼠当日摄食量下降２１．６％，次日增加１２％，以后恢复正常。ＨＩ－６１０ｍｇ／ｋｇ肌注对摄食无影响，但可部分对抗梭曼引起的摄食抑制。可能中毒早期的摄食抑制是由梭曼和阿托品共同引起的，后期则以毒剂为主，梭曼抑制摄水与抑制摄食的作用基本一致。
The effects of soman and antitoxic drugs on feeding behavior of rats were studied by recording the daily food intake of rats. The experimental results showed that 0.035 mg / kg (0.6 LD_ (50)) of intramuscular injection of mannitol reduced the daily food intake by 38.3% and inhibited the effect for 5 days. The activity of AChE in the hypothalamus decreased by 49% in the thalamus, but not completely recovered after 10 days of poisoning. Soman’s inhibition of feeding and the action time of inhibiting AChE activity were consistent. Atropine 10mg / kg intramuscular injection, can reduce the daily intake of rats 21.6%, the next day increased 12%, later returned to normal. HI-610mg / kg intramuscular injection has no effect on feeding, but can partially combat soman-induced feeding inhibition. May be poisoning early feeding inhibition is caused by soman and atropine together, the latter is dominated by poison, soman inhibition of water intake and inhibit the role of feeding basically the same.