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目的探讨硝呋太尔制霉菌素阴道栓治疗外阴阴道假丝酵母菌病合并细菌性阴道炎的疗效。方法将外阴阴道假丝酵母菌病合并细菌性阴道炎的病例150例随机分为治疗组和对照组,各75例。治疗组采用硝呋太尔制霉菌素阴道栓阴道上药,每晚1次,每次1粒,连用6 d;对照组采用传统制霉菌素栓及甲硝唑阴道泡腾片联合阴道上药,每晚1次,其中制霉菌素栓每粒50万U;甲硝唑阴道泡腾片每粒200 mg,连用7 d。进行临床疗效评价、真菌学及细菌学实验室检查,比较疗效。结果治疗组的临床治愈率和真、细菌清除率在治疗后第7天及治疗后第28天均明显优于对照组(P<0.05)。治疗依从性好且无不良反应。结论硝呋太尔制霉菌素阴道栓治疗外阴阴道假丝酵母菌病合并细菌性阴道炎可获得很好的临床疗效。
Objective To investigate the curative effect of nifurateal nystatin vaginal suppository in the treatment of vulvovaginal candidiasis with bacterial vaginosis. Methods 150 cases of vulvovaginal candidiasis with bacterial vaginitis were randomly divided into treatment group and control group, each with 75 cases. The treatment group used nifuratel nystatin vaginal suppository vaginal drug, 1 night, once every 1, once every 6 d; control group using traditional nystatin suppository and metronidazole vaginal effervescent tablets combined vaginal drug , 1 night, nystatin block each 500000 U; metronidazole vaginal effervescent tablets 200 mg each, once every 7 d. Evaluation of clinical efficacy, mycology and bacteriology laboratory tests to compare the efficacy. Results The clinical cure rate, true and bacterial clearance rate in the treatment group were significantly better than those in the control group on the 7th day and the 28th day after treatment (P <0.05). Good compliance and no adverse reactions. Conclusion Nifuratel nystatin vaginal suppository treatment of vulvovaginal candidiasis with bacterial vaginosis can be very good clinical efficacy.