膀胱过度活动症(overactive bladder syndrome,OAB)是一种以尿急症状为特征的征候群,常伴有尿频和夜尿症状,伴有或不伴有急迫性尿失禁(urge incontinence,UI)[1];尿动力学上可表现为逼尿肌过度活动(detrusor overactivity,DO),也可为其他形式的尿道-膀胱功能障碍。DO为OAB的最常见原因,50%~70%的OAB患者由此引起症状[2]。45%~50%的男性膀胱出口梗阻(bladder outlet obstruction,BOO)患者存在DO[3],而良性前列腺增生(benign prostatic hyperplasia,BPH)为老年男性引起 Overactive bladder syndrome (OAB) is a syndrome characterized by urinary symptoms associated with frequent urination and nocturia, with or without urge incontinence (UI) [1 Urodynamics can be characterized as detrusor overactivity (DO) and can be other forms of urethral-bladder dysfunction. DO is the most common cause of OAB, which causes symptoms in 50% to 70% of OAB patients [2]. 45% to 50% of male patients with bladder outlet obstruction (BOO) have DO [3], while benign prostatic hyperplasia (BPH) is caused by elderly men