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目的探讨奥曲肽对重症胰腺炎的临床治疗效果。方法选择住院治疗的60例重症胰腺炎患者,随机分为观察组和对照组,对照组用常规方法治疗,观察组在常规治疗的基础上加用奥曲肽静脉滴注,比较两组疗效、症状改善和并发症发生情况。结果观察组总有效率为83.3%,对照组为66.7%,差异有统计学意义(P<0.05);观察组患者白细胞、血淀粉酶、尿淀粉酶恢、腹痛腹胀、胰腺水肿改善和住院时间明显短于对照组(P<0.05);观察组并发症发生率为6.7%,对照组为26.7%,差异有统计学意义(P<0.05)。结论奥曲肽治疗重症胰腺炎疗效确切,值得在临床推广应用
Objective To investigate the clinical effect of octreotide on severe pancreatitis. Methods Sixty patients with severe acute pancreatitis were selected and randomly divided into observation group and control group. The control group was treated by conventional method. The observation group was given intravenous injection of octreotide on the basis of routine treatment. The curative effect and the improvement of symptoms were compared And complications occurred. Results The total effective rate was 83.3% in the observation group and 66.7% in the control group (P <0.05). The leukocyte, blood amylase, urinary amylase recovery, abdominal pain, bloating, pancreatic edema and hospital stay in the observation group (P <0.05). The incidence of complications in the observation group was 6.7% and in the control group was 26.7%, the difference was statistically significant (P <0.05). Conclusion Octreotide is effective in treating severe pancreatitis and is worthy of clinical application