患儿男,26 d,因右眼溢泪15 d,不吃、少动、皮肤黄染3 d入院。系第1胎,足月顺产,体重3 kg,生后Apgar评分1分钟、5分钟均为10分。母乳喂养,生理性黄疸已在两周内消退。母孕期健康,否认肝炎病史。生后10 d时出现右眼溢泪,近3 d不吃、少动,皮肤黄染重现,四肢凉,有右眼内眦下方隆起皮红。查体:体重2.8 kg,体温35.8℃,脉搏136 次/min,呼吸30次/min。反应差,皮肤弹性差且轻度黄染,未见淤点。右眼内眦有溢泪及 Children male, 26 d, due to tears in the right eye 15 d, do not eat, less moving, yellow skin dye 3 d admission. Department of the first child, full-term birth, weight 3 kg, Apgar score 1 minute after birth, 5 minutes are 10 minutes. Breastfeeding, physiological jaundice has subsided within two weeks. Pregnancy during pregnancy, denied the history of hepatitis. Occurred 10 days after birth, right eye overflow tears, nearly 3 d do not eat, less moving, yellow skin reappear, cold limbs, with the right eyelid bulge under the red. Examination: Weight 2.8 kg, body temperature 35.8 ℃, pulse 136 times / min, breathing 30 times / min. Poor response, poor skin elasticity and mild yellow dye, no bruising point. Right eye infantile overflowing tears and