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目的:探讨促愈汤对胃溃疡患者胃泌素及胃黏膜血管内皮生长因子水平的影响。方法:选取胃溃疡患者60例,随机分为治疗组和对照组各30例,对照组患者进行常规西药治疗,治疗组患者在此基础上加服促愈汤进行治疗,比较两组患者的治疗效果。结果:经过治疗,治疗组在降低血胃泌素含量方面与对照组无显著区别(P>0.05),在提高血管内皮生长因子血液浓度以及胃黏膜血管内皮生长因子表达水平方面较对照组效果更为显著,差异具有统计学意义(P<0.05)。结论:促愈汤对血胃泌素含量无显著影响,其提高胃溃疡愈合质量主要与提高血管内皮生长因子水平和促进胃黏膜血管内皮生长因子表达有关。
Objective: To investigate the effect of “Yue Yu Tang” on gastrin and gastric mucosal vascular endothelial growth factor in patients with gastric ulcer. Methods: Sixty patients with gastric ulcer were selected and randomly divided into treatment group and control group, with 30 cases in each group. Patients in control group were treated with routine western medicine. Patients in treatment group were treated with Juxu Decoction on the basis of this treatment. effect. Results: After treatment, the treatment group had no significant difference (P> 0.05) in reducing the level of blood gastrin compared with the control group, but increased the blood concentration of vascular endothelial growth factor and the expression level of vascular endothelial growth factor in gastric mucosa As significant, the difference was statistically significant (P <0.05). Conclusion: Guyu Decoction has no significant effect on the level of blood gastrin, and the improvement of gastric ulcer healing quality is mainly related to the increase of vascular endothelial growth factor level and the expression of vascular endothelial growth factor in gastric mucosa.