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目的汇总分析胃黏膜相关淋巴组织(MALT)淋巴瘤临床、胃镜、病理特征。方法回顾性分析经胃镜活检及手术后病理证实胃MALT淋巴瘤35例患者的临床资料。结果 35例患者临床表现及内镜下表现并无特异性,幽门螺杆茵(Hp)感染率达89.1%(31/35),胃镜下病灶好发于胃窦、胃体,但首次胃镜下活检阳性率较低,仅占48.6%(17/35)。结论胃MALT淋巴瘤临床表现无特异性,胃镜下表现多样,提高临床和胃镜医师对本病的认识以及提高胃镜下活检阳性率及活检标本加做免疫组织化学染色是诊断胃MALT淋巴瘤的关键。
Objective To summarize the clinical, gastroscopic and pathological features of gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Methods The clinical data of 35 patients with gastric MALT lymphoma confirmed by gastroscopic biopsy and postoperative pathology were analyzed retrospectively. Results The clinical manifestations and endoscopic findings of 35 patients were nonspecific. The infection rate of Helicobacter pylori (Hp) was 89.1% (31/35). Gastroscopic lesions occurred in the gastric antrum and corpus. However, the first endoscopic biopsy The positive rate was low, accounting for only 48.6% (17/35). Conclusions The clinical manifestations of gastric MALT lymphoma are nonspecific. Gastroscopy has many manifestations. It is the key to diagnose gastric MALT lymphoma that clinical and gastroscopic physicians’ understanding of the disease and the positive rate of endoscopic biopsy and biopsy specimens plus immunohistochemical staining .