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目的分析甘露醇联合口服补液盐散Ⅰ(ORSⅠ)在普通结肠镜检查前肠道准备中的临床应用价值。方法将拟行结肠镜检查的患者192例随机分为2组,每组96例,观察组服用甘露醇联合ORSⅠ,对照组服用复方聚乙二醇(PEG)电解质散。比较2组肠道清洁效果、安全性、耐受性和药品费用情况。结果观察组肠道准备有效率为95.83%,对照组为93.75%,2组排便次数和有效率比较差异均无统计学意义(P>0.05)。观察组呕吐和低血糖发生率分别为3.12%和1.04%,对照组呕吐和低血糖发生率分别为5.21%和1.04%,2组比较差异均无统计学意义(P>0.05)。观察组总费比对照组总费用便宜68.62元。结论甘露醇联合ORSⅠ可作为基层医疗机构行普通结肠镜检查前良好的肠道清洁剂。
Objective To analyze the clinical value of mannitol combined with oral rehydration salt Ⅰ (ORS Ⅰ) in intestinal preparation before colonoscopy. Methods A total of 192 patients undergoing colonoscopy were randomly divided into 2 groups (96 in each group). The observation group received mannitol combined with ORS Ⅰ. The control group received compound polyethylene glycol (PEG) electrolytes. The intestinal cleanliness, safety, tolerability and drug costs of the two groups were compared. Results The effective rate of intestine preparation was 95.83% in the observation group and 93.75% in the control group. There was no significant difference between the two groups in the number of defecation and the effective rate (P> 0.05). The incidences of vomiting and hypoglycemia in the observation group were 3.12% and 1.04% respectively. The incidences of vomiting and hypoglycemia in the control group were 5.21% and 1.04% respectively. There was no significant difference between the two groups (P> 0.05). The total cost of the observation group was 68.62 yuan less than the total cost of the control group. Conclusions Mannitol combined with ORS Ⅰ can be used as a good intestinal cleanser before primary colonoscopy in primary medical institutions.