目的 :测定复方贝芪口服液中牛磺熊去氧胆酸的含量以控制产品质量。方法 :供试品以正丁醇提取 ,2 %氢氧化钠溶液纯化 ,以正丁醇 氯仿 二乙胺 水 ( 2 0∶12∶1∶1)为展开剂 ,两次展开 ,进行双波长薄层扫描 ,检测波长 5 35nm ,参比波长 6 85nm。结果 :线性范围 1.2～ 6 .0 μg(r =0 .9994) ,平均回收率 10 1.2 % (RSD =0 .90 % ,n =5 )。结论 :该方法简便、灵敏、专属性及重现性好 ,可用于产品质量控制 Objective : To determine the content of tauroursodeoxycholic acid in compound Beiqi Oral Liquid to control the product quality. Method: The test sample was extracted with n-butanol and purified with 2% sodium hydroxide solution. n-butanol-chloroform diethylamine water (2 0:12:1:1) was used as a developing agent and developed twice. Layer scanning, detection wavelength 5 35nm, reference wavelength 6 85nm. Results: The linear range was 1.2 to 6.0 μg (r = 0.994) and the average recovery was 10 1.2 % (RSD = 0.90%, n = 5). Conclusion: This method is simple, sensitive, specific and reproducible, and can be used for product quality control.