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目的评价包皮环切(MC)预防艾滋病在广西吸毒人群中的推广效果。方法采用整群抽样的方法抽取广西南宁市、柳州市4个美沙酮门诊共490名艾滋病病毒(HIV)阴性的男性吸毒者为研究对象,基线调查后1个月进行MC预防艾滋病宣传和干预,愿意手术且无手术禁忌症者则实施MC,干预后第9个月随访,了解研究对象对MC预防艾滋病知、信、行的变化情况。结果干预后,与基线比较,吸毒人群中MC接受意愿从56.1%上升到66.1%(χ2=9.769,P=0.002),手术率从0上升到22.8%(χ2=125.662,P=0.000);知晓MC可以预防艾滋病及其他性传播疾病从29.2%上升到70.5%(χ2=160.499,P=0.000),知晓MC可以保护性伴生殖卫生与健康从33.7%上升到随访的68.1%(χ2=111.148,P=0.000),知晓MC可以预防生殖器炎症或肿瘤从33.1%上升到63.2%(χ2=85.502,P=0.000)。结论 MC预防AIDS的推广可提高吸毒人群对MC的知晓情况、手术意愿和手术率。
Objective To evaluate the effectiveness of circumcision (MC) in preventing HIV / AIDS among drug users in Guangxi. Methods A total of 490 HIV-negative male drug users from 4 methadone clinics in Nanning and Liuzhou of Guangxi were enrolled in the study by cluster sampling method. One month after the baseline survey, we conducted a publicity and intervention on MC prevention of AIDS. The patients who underwent surgery without contraindications were followed up for MC, and the 9th month after the intervention was followed up to find out the changes of the subjects’ knowledge, letter and practice on AIDS prevention. Results After intervention, compared with baseline, the willingness of MC in drug addicts increased from 56.1% to 66.1% (χ2 = 9.769, P = 0.002), and the operative rate increased from 0 to 22.8% (χ2 = 125.662, P = 0.000) MC was able to prevent AIDS and other sexually transmitted diseases from rising from 29.2% to 70.5% (χ2 = 160.499, P = 0.000), and MC was able to increase sexual health and reproductive protection from 33.7% to follow-up 68.1% (χ2 = 111.148, P = 0.000), knowing that MC prevented genital inflammation or tumors from rising from 33.1% to 63.2% (χ 2 = 85.502, P = 0.000). Conclusion The promotion of MC in preventing AIDS can improve the knowledge of MC, the intention of surgery and the rate of operation in drug addicts.