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细胞周期是细胞生命活动的基本过程,机体中存在着精密的机制参与这一过程的调控,目前最令人瞩目的是cyclin CDK CKI组成的复杂分子网络。p27kip1是CIP/KIP家族的主要成员,传统的观点认为p27kip1仅作为CDK的抑制因子参与细胞周期的负向调控,但有证据表明在特定的条件下p27ki
Cell cycle is the basic process of cell life activities. There are sophisticated mechanisms in the body involved in the regulation of this process. At present, the most notable molecular network is the complex molecular network of cyclin CDK CKI. p27kip1 is a major member of the CIP / KIP family. The traditional view that p27kip1 is only involved in the negative regulation of cell cycle as a suppressor of CDK, but there is evidence that under certain conditions p27ki