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目的:探讨老老年高血压患者颈动脉病变与血压变异的关系。方法:将入选的64名老老年原发性高血压患者依据颈动脉超声检查结果分为颈动脉病变组和无颈动脉病变组,行24 h动态血压检查,分析两组间全天24 h收缩压变异、24 h舒张压变异、白昼收缩压变异、白昼舒张压变异、夜间收缩压变异、夜间舒张压变异的差异。结果:颈动脉病变组24 h收缩压变异、24 h舒张压变异、白昼收缩压变异、夜间收缩压变异、夜间舒张压变异明显高于无颈动脉病变组(14.09±2.67 vs 8.88±1.19,12.42±3.08 vs 10.22±2.80,11.71±3.20 vs 8.44±1.80,11.40±10.70 vs 6.82±2.65,10.52±3.50 vs 8.29±2.62;P<0.01或P<0.05)。结论:老老年高血压患者的颈动脉病变与血压变异密切相关。
Objective: To investigate the relationship between carotid artery disease and blood pressure variation in elderly patients with hypertension. Methods: Sixty-four elderly patients with essential hypertension were divided into carotid artery disease group and non-carotid artery disease group according to carotid artery ultrasonography. The ambulatory blood pressure was measured 24 hours. Pressure variation, 24 h diastolic pressure variation, daytime systolic pressure variation, daytime diastolic pressure variation, nighttime systolic pressure variation, and nighttime diastolic pressure variability. Results: The changes of systolic pressure at 24 h, diastolic pressure at 24 h, systolic pressure at daytime, systolic pressure at night and diastolic pressure at night were significantly higher in patients with carotid artery disease than those without carotid artery disease (14.09 ± 2.67 vs 8.88 ± 1.19, 12.42 ± 3.08 vs 10.22 ± 2.80, 11.71 ± 3.20 vs 8.44 ± 1.80, 11.40 ± 10.70 vs 6.82 ± 2.65, 10.52 ± 3.50 vs 8.29 ± 2.62; P <0.01 or P <0.05). Conclusion: The carotid artery lesions in elderly patients with hypertension are closely related to the variation of blood pressure.