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经肝脏活检标本病理和实验室证实的30例慢性活动性乙型病毒性肝炎病人,轻型病理变化(以肝小叶周边碎屑样坏死为特征)22例,中型(以肝小叶桥形坏死为特征)3例,重型(整个肝小叶结构明显破坏为特征)5例。经肝细胞免疫组织化学检测证实:HBsAg在肝细胞内的分布与肝细胞病理损伤程度呈负相关。病
Thirty cases of chronic active hepatitis B virus confirmed by pathology of liver biopsy specimens and laboratory confirmed 22 cases of light pathological changes (characterized by debris-like necrosis around hepatic lobule), and medium (characterized by hepatic lobule necrosis) ), 3 cases of heavy (the entire structure of the hepatic lobule is characterized by significant damage) in 5 cases. Immunohistochemical detection of liver cells confirmed that the distribution of HBsAg in hepatocytes was negatively correlated with the degree of hepatocyte pathological damage. disease