论文部分内容阅读
目的观察综合干预治疗对高血压患者疗效的影响。方法采用随机平行对照临床试验,选200例高血压患者且具有至少下列1项可干预的危险因素:①血脂异常:总胆固醇(TC)≥5.7mmol/L;②糖尿病:空腹血糖(FPG)≥7.0mmol/L或(和)餐后2h血糖(2hPG)≥11.1mmol/L;③肥胖:体质指数(BMI)≥28kg/m2。随机分成严格治疗组及随意治疗组。监测血压、血脂、血糖变化及并发症发生率。结果严格干预治疗组的血压、血糖及血脂水平的控制效果均优于随意治疗组(P<0.05);严格干预治疗组脑出血、脑梗死、急性心肌梗死、脑卒中发病率及死亡率明显低于随意治疗组(P<0.05)。结论综合干预对控制高血压、血糖及血脂有重要作用,综合干预治疗高血压是预防脑出血、脑梗死、急性心肌梗死、脑卒中等心脑血管事件的有效手段。
Objective To observe the effect of comprehensive intervention on the curative effect of patients with hypertension. Methods Randomized controlled clinical trials were conducted in 200 hypertensive patients with at least one of the following interventional risk factors: ① dyslipidemia: total cholesterol (TC) ≥ 5.7 mmol / L; ② diabetes: fasting plasma glucose (FPG) ≥ 7.0mmol / L or (and) postprandial 2h blood glucose (2hPG) ≥11.1mmol / L; ③ obesity: body mass index (BMI) ≥ 28kg / m2. Randomly divided into a strict treatment group and random treatment group. Blood pressure, blood lipids, blood glucose and complications were monitored. Results The results showed that the control effect of blood pressure, blood glucose and blood lipid level were significantly better than those of the randomized treatment group (P <0.05). The incidence of cerebral hemorrhage, cerebral infarction, acute myocardial infarction, stroke and mortality were significantly lower in the severe intervention group In the randomized treatment group (P <0.05). Conclusion Comprehensive intervention plays an important role in the control of hypertension, blood glucose and lipids. Comprehensive treatment of hypertension is an effective way to prevent cardiovascular and cerebrovascular events such as cerebral hemorrhage, cerebral infarction, acute myocardial infarction and stroke.